Ly and Ia antigen phenotypes of T cells involved in delayed-type hypersensitivity and in suppression

نویسندگان

  • M A Vadas
  • J F Miller
  • I F McKenzie
  • S E Chism
  • F W Shen
  • E A Boyse
  • J R Gamble
  • A M Whitelaw
چکیده

The Ly and Ia phenotypes of T lymphocytes involved in different functions were characterized by the use of specific antisera. T cells responsible for delayed-type hypersensitivity (DTH) and for helper functions were found to be Ly-1+,2- in contrast to cytotoxic T cells and T cells responsible for suppression of antibody responses which were Ly-1-,2+. Unlike some primed helper cells, T cells involved in DTH were Ia-. Suppressor cells in the system were Ia+.

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عنوان ژورنال:
  • The Journal of Experimental Medicine

دوره 144  شماره 

صفحات  -

تاریخ انتشار 1976